Systemic Lupus Erythematosus - SLE

A chronic, long-lasting systemic autoimmune disease that happens when the body's immune system attack it's own tissues and organs. In some, this might cause permanent tissue damage. Many different body sytems can get affected by inflammation caused by Lupus(SLE)- joints, skin, kidneys, blood cells, brain, heart and lungs.

To diagnose SLE, it can be difficult as the signs and symptoms often mimic other ailments. It is different for every person, range from mild to severe. The most distinctive sign by SLE - a facial rash that resembles wings of butterfly unfolding across both cheeks - occurs in many but not all cases. Anyone can get SLE, either genetics or more likely to be triggered by factors - infections, drugs, sunlight. Women has HIGHER risk than Men do, it is about 9:1 - as a factor of hormonal and sex chromosome differences.

Discoid Lupus Erythematosus

A chronic autoimmune disease that affects the skin. The name of the disease is regarding the coin-shaped lesions it produces. The condition shows a severe rash that has high tendency to worsen after an exposure to sunlight. The rash can appear anywhere on the body - ecspecially sclap, neck, hands and feet - that has the ability to permanent scar, hyperpigmentation and hair loss. The exact causes still has not been found as it is an autoimmune disease. Generally, the combination of genetics and enivironmental do triggers. This DSE do not pass from one person to another.

It should not be confused with Systemic Lupus Erythematosus(SLE)!
Here are the differences,

Systemid Lupus Erythomatotus Discoid Lupus Erythomatotus
More malignant More benign
Affect any part of the body Affect the skin only
Skin symptom less severe Skin symptom more severe
Include internal organ Does not include internal organ
No cure yet Can clear up completely if treated early

Neonatal Lupus Erythematosus

The name itself is not as if it the infant form of lupus but the skin rashes that resembles the one associated with Lupus. It is a rare acquired Lupus that present at birth. Affected ones always develop a characteristics red rash or skin eruption. The most significant potential complication is Congenital Heart Block . This does not revolve within the first few months of life instead infants may instantly require pacemaker. Some of them only develop skin symptoms, some may develop only heart symptoms and less often some develop both. This is result from specific autoantibodies that travel across placenta from a pregnant mother to her developing fetus. This disease causes damage to specific fetal tissue through a process that is not fully understood.